Bone tissue engineering
Biomimetic scaffolds of chitosan, alginate–fucoidan and nano-hydroxyapatite that guide osteogenic differentiation of mesenchymal stem cells and bone regeneration.
Research
We investigate and develop materials from marine and natural sources for biomedical applications — with a focus on tissue engineering, drug delivery and artificial organs.
Themes
Research areas
Marine-derived biomaterials
Turning seaweed polysaccharides, marine collagen and fish-bone hydroxyapatite into high-value materials for medicine.
Drug delivery systems
Polysaccharide nanoparticles, liposomes and composite beads for controlled release of drugs and growth factors.
Antimicrobial biomaterials
Green-synthesised metal nanoparticles and functional coatings to tackle antimicrobial resistance.
Biomaterials for artificial organs
Designing biocompatible materials and constructs aimed at transplant and artificial organ applications.
Biosensors
Nanomaterial-based sensing platforms for biomedical diagnostics.
Approach
From natural resources to clinical materials
Marine organisms are a rich, sustainable source of biopolymers and bioceramics. We isolate and characterise these materials, combine them into nanocomposites and scaffolds, and test how cells — especially mesenchymal stem cells — respond to them.
Promising materials move on to drug-delivery studies, antimicrobial testing and in vivo bone-formation models in collaboration with clinical and engineering partners.
Materials & systems we work with
Chitosan & chitooligosaccharidesAlginate–fucoidan compositesMarine collagenFish bone-derived hydroxyapatiteSeaweed polysaccharidesNano-bioceramicsGraphene oxide & carbon nanotubesTransition metal dichalcogenidesGreen-synthesised nanoparticlesMesenchymal stem cells
In progress
Current & recent projects
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DST-SERB · 2022Biocomposites based on Liquid Exfoliated Transition Metal Dichalcogenides for Orthopaedic Applications: Osteogenic Differentiation of Mesenchymal Stem Cells, and Bone Formation Study in Rabbit Models
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DST-SERB · 2019Fucoidan beads containing hydroxyapatite and graphene oxide for bone tissue repair and regeneration
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DBT-BIRAC · 2020Mosquito-repellent military uniform impregnated with micro-encapsulated formulations through a novel pressure plasma technique
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DBT-BIRAC · 2021An innovative approach to design the save appliance, Maxillary Protraction Device
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Yenepoya (Deemed to be University) · 2019Seaweed polysaccharides for bone tissue regeneration